People with bipolar disorder may have a higher risk of certain side effects with Contrave. If you have bipolar disorder, talk with your doctor about your condition before starting Contrave. Also, tell your healthcare professional about any other health conditions you might have and any other medicines you take. This includes medicines available without a prescription and supplements. To help avoid interactions, your doctor should manage all of your medications carefully.
You can ask them about other treatments that may be better options for you. Nortriptyline belongs to a class of drugs called tricyclic antidepressants. A class of drugs is a group of medications that work in a similar way. Many other medicines may alter the blood levels of nortriptyline, and vice versa.
You may have trouble concentrating or performing mechanical skills. Small amounts of alcohol can make it dangerous to drive, and when you mix alcohol with certain medicines you put yourself at even greater risk. Combining alcohol with some medicines can lead to falls and serious injuries, especially among older people. This activity provides 0.75 CME/CE credits for physicians, physician assistants, nurses, pharmacists, and psychologists, as well as other healthcare professionals whose licensing boards accept APA or AMA credits. Several over-the-counter and prescription products contain acetaminophen.
Warnings for people with certain health conditions
- This is because women’s bodies generally have less water than men’s bodies.
- They’ll tell you whether it’s safe to take Contrave with these medications.
- Seven subjects had a positive response of a 30 mm Hg increase in SBP during both placebo and treatment phases, suggesting that the result may have been related to other factors.
- The type of liver damage from misuse of alcohol and acetaminophen is called acute liver damage.
- Certain medical conditions or other health factors may raise the risk of interactions with Trintellix.
Another widely used RA drug, baricitinib, could be an exception as it was cleared by kidneys with minimal mediation by CYP3A4, and thus, the CBD interaction could be minimal. A Target-mediated drug–drug interactions of cannabidiol with cannabinoid and 5-hydroxytryptamine 1A receptors27. B Target-mediated drug–drug interactions of cannabidiol with 5-hydroxytryptamine 2A receptors27. C Target-mediated drug–drug interactions of cannabidiol with 5-hydroxytryptamine 3A receptors27. D Target-mediated drug–drug interactions of cannabidiol with prostaglandin G/H synthase 1 and 2 inhibitors27. E Target-mediated drug–drug interactions of cannabidiol with Cytochrome P450 1B1 and 3A5 inhibitor27.
Alcohol-Medication Interactions: Potentially Dangerous Mixes
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances. Cough syrup and laxatives may have some of the highest alcohol concentrations. Contributors to this article for the NIAAA Core Resource on Alcohol include the writer for the full article, content contributors to subsections, reviewers, and editorial staff. These contributors included both experts external to NIAAA as well as NIAAA staff. Consider reducing the dose of sensitive CYP2C19 substrates, as clinically appropriate, when co-administered.
Both Contrave and amantadine can increase the level of a certain chemical called dopamine in your body. Having a high level of dopamine can raise your risk of side effects from either drug. Examples of these side effects include dizziness, agitation, and restlessness.
More common side effects
It has also been postulated that such a reaction may be due to isoniazid’s inhibition of monoamine oxidase, as symptoms have been reported after consumption of wine (109). Isoniazid was found to alter central monoaminergic neurotransmission (111). Although aldehyde dehydrogenase was inhibited with coadministration, blood acetaldehyde levels were not increased. In addition to the pharmacodynamic interactions, pharmacokinetic interactions between alcohol and phenobarbital exist, because alcohol inhibits the medication’s breakdown in the liver.
Follow your doctor’s orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so. Alcohol is broken down to acetaldehyde either by alcohol dehydrogenase (ADH) or cytochrome P450 (CYP). The acetaldehyde then is broken down to acetic acid and water by two variants of the enzyme aldehyde dehydrogenase (ALDH).
Side Effects of Pamelor
If you have bulimia or anorexia or have had these conditions in the past, your doctor likely won’t prescribe Contrave for you. These conditions can increase your risk of seizures from Contrave. If you have questions about drug interactions that may affect you, talk with your doctor or pharmacist. If you take an MAOI or have taken one in the past 14 days, your doctor likely won’t prescribe Contrave for you. (MAOIs are used to treat depression, certain infections, and certain blood disorders.) Taking an MAOI with Contrave could raise your risk of severely high blood pressure. (An active ingredient is what makes a drug work.) If you take other drugs that contain bupropion, your doctor likely won’t prescribe Contrave for you.
For this reason, it’s still important to check with your doctor or pharmacist before taking any of these products while taking Contrave. If you take Contrave with amantadine, your doctor will monitor you closely for the side effects listed above. Be sure to tell them if you have these side effects while taking the drugs together. Taking Contrave with amantadine (Gocovri) can increase the risk of side effects from Contrave and amantadine.
Another combination drug called phentermine/topiramate (Qsymia) is approved for weight loss in adults and in children ages 12 years and older molly drug wiki with obesity. It’s important to note that this drug can cause harm to a fetus, so your doctor may not recommend it if you can become pregnant. A group of diabetes drugs called GLP-1 receptor agonists can be used in people with or without diabetes. These drugs include liraglutide (Saxenda) and semaglutide (Wegovy) and should be taken along with a balanced diet and exercise. Cannabis (commonly called marijuana) and cannabis products, such as cannabidiol (CBD), have been specifically reported to interact with Contrave.
